Open AccessGenome-wide CRISPR screens identify ferroptosis as a novel therapeutic vulnerability in acute lymphoblastic leukemia
Author(s) -
Marie-Eve Lalonde,
Marc Sasseville,
Anne-Marie Gélinas,
Jean-Sébastien Milanese,
Kathie Béland,
Simon Drouin,
Élie Haddad,
Richard Marcotte
Publication year - 2022
Publication title -
haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.782
H-Index - 142
eISSN - 1592-8721
pISSN - 0390-6078
DOI - 10.3324/haematol.2022.280786
Subject(s) - crispr , biology , cancer research , lymphoblastic leukemia , gene , gpx4 , genome editing , bystander effect , genome , leukemia , genetics , oxidative stress , immunology , biochemistry , catalase , glutathione peroxidase