Mutational analysis in serial marrow samples during azacitidine treatment in patients with post-transplant relapse of acute myeloid leukemia or myelodysplastic syndromes | Zendy

Janghee Woo | Zendy; Nicholas P. Howard | Zendy; Barry E. Storer | Zendy; Min Fang | Zendy; Cecilia C.S. Yeung | Zendy; Bart L. Scott | Zendy; H. Joachim Deeg | Zendy

Open Access

Mutational analysis in serial marrow samples during azacitidine treatment in patients with post-transplant relapse of acute myeloid leukemia or myelodysplastic syndromes

Author(s) -

Janghee Woo,

Nicholas P. Howard,

Barry E. Storer,

Min Fang,

Cecilia C.S. Yeung,

Bart L. Scott,

H. Joachim Deeg

Publication year - 2017

Publication title -

haematologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.782

H-Index - 142

eISSN - 1592-8721

pISSN - 0390-6078

DOI - 10.3324/haematol.2016.162909

Subject(s) - azacitidine , myelodysplastic syndromes , myeloid leukemia , medicine , oncology , myeloid , leukemia , decitabine , bone marrow , biology , dna methylation , gene , genetics , gene expression

Post-transplant relapse remains a major cause of treatment failure in patients with myeloid malignancies such as myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML). Despite interventions such as withdrawal of immunosuppression, administration of chemotherapy, donor lymphocyte infusion (

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