Open AccessArticular Cartilage: The Destruction of Bilayers and Deactivation of Phospholipid Molecules
Publication year - 2018
Publication title -
advances in theoretical and computational physics
Language(s) - English
Resource type - Journals
ISSN - 2639-0108
DOI - 10.33140/atcp/01/02/00001
Subject(s) - phospholipid , chemistry , biophysics , membrane , lipid bilayer , molecule , biochemistry , organic chemistry , biology
To our knowleadge the coaugulation by interacton of β2 -Glycoprotein I (β2 -GP I) with the phospholipid membrane is required to verify this hypothesis. The open hockey stick-like conformation occurs when protonated amino acid functional group (-NH3 +) β2-GP I is complexed to negatively charged phospholipids functional group (-PO4 - ) resulting in the destruction of bilayers and the deactivation of phospholipid molecules.