Open AccessSecond‐Trimester Abortion by Extra‐Amniotic Instillation of Rivanol Combined with Intravenous Administration of Oxytocin or Prostaglandin F 2α
Author(s) -
Klinte Ingemar,
Hamberger Lars,
Wiqvist Nils
Publication year - 1983
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348309156226
Subject(s) - medicine , oxytocin , abortion , pregnancy , prostaglandin , misoprostol , anesthesia , prostaglandin f , obstetrics , genetics , biology
Abstract. Induction of second‐trimester abortion was studied by administration of the acridine derivative Rivanol in combination with an i.v. drip infusion of oxytocin or pros‐taglandin F 2α (PG 2α ), alone or in combination. It was found that an early onset of the i.v. infusion was of major importance for the outcome. Administration of oxytocin in immediate connection with the Rivanol instillation proved more favorable than administration of PGF 2α ) or a combined oxytocin PGF 2α drip, taking into consideration the induction‐abortion time as related to the side effects. A lag phase between the instillation of Rivanol and the start of i.v. infusion such as has earlier been frequently recommended seemed to be of no specific advantage, but caused both a prolonged induction‐abortion time and an increased incidence of infection.