Open AccessThe Behaviour of Microsomal Mono‐Electron Carriers in Human Placenta During Late Pregnancy
Author(s) -
Paparella P.,
Castaldo F.,
Galeotti T.,
Bompiani A.,
Terranova T.
Publication year - 1976
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347609158510
Subject(s) - medicine , placenta , pregnancy , obstetrics , human placenta , microsome , andrology , gynecology , fetus , biochemistry , enzyme , biology , genetics
Abstract. The activities and the content of enzymes involved in mixed function oxidase systems (cytochromes P‐450 and b 5 , NADPH‐cytochrome c reductase and NADH cytochrome b 5 reductase) in microsomes from 114 human placentae were found to increase from the 34th up to the 38th–39th week of gestation and later to decrease until the 43rd week. Such a process can be related to the following: (i) the phospholipid content of microsomal membranes; (ii) the protein synthesis possibly induced by steroids such as androstenedione and testosterone.