
Leucine Aminopeptidase Activity in Maternal, Cord Blood and Placenta of Normal Pregnancy and in Pre‐Eclampsia
Author(s) -
Ibrahim Fawzia K.,
Fattah Mohamed M. A.,
Ramadan Mohyi A.,
Sammour Mohamed B.
Publication year - 1976
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347609156782
Subject(s) - medicine , placenta , cord blood , pregnancy , aminopeptidase , eclampsia , fetus , preeclampsia , obstetrics , cord , umbilical cord , leucine , endocrinology , immunology , biochemistry , surgery , biology , amino acid , genetics
. I) Leucine aminopeptidase (LAP) was determined in maternal and fetal blood and in the placenta of mild and severe pre‐eclamptic patients, then compared to the levels of normal pregnancy. 2) The enzyme activity increased significantly in severe pre‐eclampsia as compared with the mild type and with normal pregnancy. 3) In mild pre‐eclamptic patients LAP activity of maternal and cord blood did not increase significantly as compared with the normal cases but the placenta showed a slight decrease. 4) The enzyme level in cord blood did not increase markedly in pre‐eclampsia.