Open AccessDetermination Of 6‐Pgdh in the Vaginal Secretions of Patients with Carcinoma of the Cervix: A New Method of Collection of Vaginal Secretions
Author(s) -
Hasch E.,
Sørensen B.,
Laursen Th.
Publication year - 1971
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347109157283
Subject(s) - medicine , cervix , carcinoma , gynecology , cancer , gastroenterology
Determinations of 6‐phosphorgluconate‐dehydrogenase concentration of vaginal secretions were made in 107 women, in 37 of whom carcinoma of the cervix was, subsequently, histologically confirmed. The aim was to determine the value of this enzyme assay in the detection of carcinoma of the cervix. In normal group, there were 35% false positive findings, while in the carcinoma group there were 15% false negative findings. It is concluded that the method, at least in its present form, is not of value in the diagnosis of carcinoma. A new filter technique for collection of vaginal secretions was used, which is recommended for future similar studies.