Open AccessAnalysis of procalcitonin and urine nitrite to predictor sepsis patients
Author(s) -
Andi Itha Maghfirah,
Rachmawati Muhiddin,
Irda Handayani,
Nursin Abdul Kadir
Publication year - 2021
Publication title -
medisains
Language(s) - English
Resource type - Journals
eISSN - 2621-2366
pISSN - 1693-7309
DOI - 10.30595/medisains.v19i2.11075
Subject(s) - procalcitonin , sepsis , urine , nitrite , medicine , urinary system , gastroenterology , chemistry , nitrate , organic chemistry
Background: Sepsis is a significant health problem worldwide. Various sepsis biomarkers have been studied before, but few data link PCT and urinary nitrite levels to culture result in septic patients.Purposes: This study compares PCT, Urine Nitrite on culture results against their sensitivity to determine variables that can be used to predict sepsis patients.Methods: This is a cross-sectional study by taking data on patients with sepsis aged ≥18 years in 207. Diagnostic tests were performed to determine sensitivity and specificity of PCT, Urine Nitrite, and Blood Culture of septic patients. A Chi-square test was carried out to see the relationship between two parameters and the outcome of sepsis.Results: PCT sensitivity was higher than Urine Nitrite: 74.5%. Specificity of Urine Nitrite was higher than PCT: 88.2%. Procalcitonin has a significant relationship with sepsis patient outcomes (p<0.005).Conclusion: PCT can predict septic patients because it has a higher sensitivity than urine nitrite