Open AccessIL-7RA alleles on the risk of Multiple Sclerosis in Turkish population
Author(s) -
Miraç Ayşen Ünsal,
Nüket Yıldız Manukyan,
Nihal Işık,
Güher Saruhan Direskeneli
Publication year - 2018
Publication title -
nöropsikiyatri arşivi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 14
ISSN - 1309-4866
DOI - 10.29399/npa.23437
Subject(s) - turkish population , multiple sclerosis , genotype , allele , turkish , polymorphism (computer science) , disease , genetics , medicine , gene , biology , immunology , linguistics , philosophy
The T244I variant of the IL-7RA gene, rs6897932, is one of the first polymorphisms found to be associated with the development of multiple sclerosis (MS). Although several studies provided evidence for the association of MS and this variant, other studies could not confirm this result. These inconsistent results suggest that the role of this polymorphism in the development of disease is associated with ethnicity.