Open AccessSynthesis , Identification And Evaluation Of Antibacterial Activity For Some New Heterocyclic Derivatives From 4-Methoxy-2-Nitroaniline
Author(s) -
Sabah Matrood Mezaal,
Shaimaa Adnan
Publication year - 2021
Publication title -
mağallaẗ al-qādisiyyaaẗ li-l-ʻulūm al-ṣirfaẗ
Language(s) - English
Resource type - Journals
eISSN - 2411-3514
pISSN - 1997-2490
DOI - 10.29350/qjps.2021.26.4.1383
Subject(s) - chemistry , anthranilic acid , imine , quinazoline , combinatorial chemistry , organic chemistry , amine gas treating , derivative (finance) , catalysis , financial economics , economics
This research involved synthesis. novel heterocyclic derivatives (quinazoline and thiazinone) derivatives , this compounds prepared from starting react (4-methoxy-2-nitroaniline) with 2,4-dimethoxyacetophenone to gate azo derivative (A) , (A) interact with aromatic amine derivatives to produce imine compounds (B1-B2), imine derivatives interact with (anthranilic acid , 2-mercaptobenzoic) to get heterocyclic derivatives quinazoline (C1-C2) and thiazinone (D1-D2 ) . All these compound characterized by13 C-NMR , FT-IR , 1HMNR . Then that,we studies the,biological,properties for,all heterocyclic derivatives,to,ward.two different kindof bacteria.