Open AccessSPONTANEOUS BACTERIAL PERITONITIS (SBP)
Author(s) -
Waseem Sarwar Malghani,
Farooq Mohyud Din Chaudhary,
Muhammad Ilyas,
Asma Tameez Ud Din,
Asim Tameez Ud Din
Publication year - 2018
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2018.25.05.320
Subject(s) - medicine , spontaneous bacterial peritonitis , cirrhosis , ascites , gastroenterology , antibiotics , aseptic processing , peritonitis , liver disease , surgery , microbiology and biotechnology , biology
Background: Spontaneous bacterial peritonitis (SBP) is a bacterial infectionwhich occurs in cirrhosis of liver complicated by ascites. To decrease the high in-hospitalmortality rate of 20 to 30%, rapid diagnosis and antibiotic treatment are essential. Objectives:To ascertain the frequency of causative organisms of SBP. Study Design: Descriptive study.Setting: Gastroenterology Department, Nishtar Medical College/Hospital, Multan using nonprobability, consecutive sampling. Period: Jan 2017 to July 2017. Methodology: The studyincluded 183 patients of liver cirrhosis having SBP. Under aseptic conditions, ascitic fluid tapwas done and sent for bacterial culture. Data was analyzed by computer program SPSS-18.Results: Of these 183 study cases, 103 (56.3%) were male patients while 80 (43.7%) werefemale patients. Mean age of our study cases was 51.73 ± 9.28 years. Mean duration ofdisease (liver cirrhosis) was 26.43 ± 12.32 months while mean duration of SBP was 4.51 ±1.21 days. More than half of cases (56.3%) of liver disease were caused by Chronic Hepatitis C,13.7% were due to Hepatitis B and 16.9% of patients were alcoholics. Among the study cases,E.coli was noted in 135 (73.8%), Staph. Aureus in 17.5% and Klebsiella was noted in 8.7%.Conclusion: Our study indicates that E.coli is the major organism causing SBP in patientshaving cirrhosis of liver followed by Staph. Aureus and Klebsiella.