Open AccessSURGICAL SITE INFECTION
Author(s) -
Ahmad Faraz,
Abdul Hameed,
Fazal Bari,
Irum Sabir Ali,
Hamzullah Khan,
Amjad Naeem,
Mumtaz Khan,
Abid Hussain,
Khyber Girls
Publication year - 2015
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2015.22.03.1355
Subject(s) - ceftriaxone , medicine , klebsiella pneumoniae , bacteria , enterobacter , klebsiella , microbiology and biotechnology , antibiotics , escherichia coli , biology , biochemistry , genetics , gene
Ceftriaxone is used in wide range of day to day microbial infections in clinicalpractice3. Despite the incumbent drug regulating authority in Pakistan, there is scanty literaturecomparing the anti-microbial efficacy of different available brands of ceftriaxone. Objectives:To know the in-vitro activity of various brands of ceftriaxone against bacteria most commonlyisolated from surgical site infection (SSI). A comparison of five days cost of these brands willalso be done. Design: Experimental study. Period: Feb 2013 to Aug 2013 Setting: Surgical“C” unit Lady Reading Hospital (LRH) in collaboration with departments of pharmacologyKhyber Girls Medical College (KGMC) and microbiology department of Lady Reading HospitalPeshawar. Material & Methods: Isolates of five bacteria i.e. Staphylococcus aureus, Proteusmirabilis, Escherischia coli, enterobacter Spp, and Klebsiella pneumoniae, found sensitive toceftriaxone were grown on 50 slops each and the zone of inhibition was checked for each ofthe ten brands of ceftriaxone. Results: The zones of inhibitions of different brands of ceftriaxoneagainst the above mentioned bacteria were not significantly different. The cost of therapy wassignificantly different for ten brands. Conclusions: Various brands of ceftriaxone of variablecost had no influence on their activity against bacteria involved in SSI.