Open AccessADRENALINE;
Author(s) -
Naseer Khan Baloch,
Nusrat Jafri,
Ahmed Danyal
Publication year - 2014
Publication title -
the professional medical journal/the professional medical journal
Language(s) - English
Resource type - Journals
eISSN - 2071-7733
pISSN - 1024-8919
DOI - 10.29309/tpmj/2014.21.06.2163
Subject(s) - inotrope , medicine , metoprolol , stimulation , adrenergic receptor , cardiology , endocrinology , receptor
There is no doubt that the effects of the catecholamines of the heart are mainly due to the stimulation of β-adrenoceptors but in the mid 1960’ s the first evidence was presented that a-adrenoceptors mediating positive inotrpoism exists also in the myocardium beside well established β -adrenoceptors. In our observation adrenaline shows a positive inotropic response. The response of adrenaline in presence of metoprolol (β1blocker) showed negative inotropic effect.