CANCER TYPES;

Introduction: This study attempts to highlight the relation of various types ofcancers to abnormalities in liver and renal function tests. Objectives: Correlation of derangedrenal and liver function tests to different types of cancers in industrial workers who are exposed toindustrial chemicals and carcinogens. Patients and Methods: This non-interventional studyincluded 100 hundred confirmed cases of cancer were selected and studied from July 2011 toDecember 2011. The study was conducted at Fatima Memorial Hospital/College of Medicine &Dentistry, Lahore . Results: Out of these 100 patients, 21 had CA lung, 19 had lymphoma, 14 hadsarcoma, 13 had CA breast, 6 had CA prostate, 4 had CA liver, 3 had CA colon, 3 had CA ovary, 3had CA testis, 2 had leukemia, 2 had multiple myeloma, 2 had CA gall bladder, 2 had CA stomach,1 had CA esophagus, 1had CA tongue, 1had CA parotid, 1 had CA rectum, 1 had CA cervix and 1had CA larynx. Among lymphoma, non-Hodgkin lymphoma was more than Hodgkin lymphoma(out of 19 patients, 13 had non-Hodgkin and 6 had Hodgkin lymphoma). Out of 14 patients ofsarcomas, 5 had Ewing sarcoma, 4 had chondrosarcoma, 3 had fibrosarcoma and 2 hadliposarcoma. Similarly the serum bilirubin levels in liver cancer, ovarian cancer, multiplemyeloma, stomach and gall bladder cancer were 1.50±0.31, 1.17±0.10, 1.46±0.15 and1.40±0.50 mg% were 32.38±18.81, 37.73±4.35, 34.43±4.35, 45.00±46.17, 31.33±44.70,65.25±31.14, 33.67±80.90, 99.00±73.08, 50.00±98.49, 33.50±75.0, 36.50±85.0 and49.0±11.0 μ/l respectively which were statistically significantly higher (p<0.05) then controlindividuals. respectively which were significantly higher (p<0.05) than the control individualsSimilarly the ALT levels in lung cancer, lymphoma, sarcoma, breast cancer , prostate cancer, livercancer, leukemia, ovarian cancer, cancer of colon, multiple myeloma, cancer of testis andstomach. The mean serum creatinine levels in lung cancer, liver cancer and cancer of colon were0.89±0.05, 0.90±0.16 mg% respectively which were significantly higher than the controlindividuals (p<0.05). Conclusions: The renal and liver function tests should be frequentlymonitored in cancer patients from industrial back grounds.