Open AccessUji Antibakteri Ekstrak Metanol Kulit Buah Manggis (garcinia mangostana l.) Terhadap Staphyllococcus aureus dan Escherechia coli
Author(s) -
Sujono Sujono,
Anik Nuryati
Publication year - 2017
Publication title -
jurnal teknologi laboratorium/jurnal teknologi laboratorium
Language(s) - English
Resource type - Journals
eISSN - 2580-0191
pISSN - 2338-5634
DOI - 10.29238/teknolabjournal.v6i1.60
Subject(s) - garcinia mangostana , staphylococcus aureus , antibacterial activity , xanthone , bark (sound) , chemistry , traditional medicine , agar diffusion test , bacteria , microbiology and biotechnology , food science , biology , medicine , stereochemistry , ecology , genetics
Alfa mangostin, gamma-mangostin and xanthone group compounds are secondary metabolites contained in mangosteen (G. mangostana L.) which can be isolated from the fruit, bark, leaves and rind of mangosteen. All three compounds were shown to inhibit stronger against Mycobacterium tuberculosis. Alfa mangostin also active against Staphylococcus aureus and Enterococcus bacteria that are resistant to vancomisin and methicillin. Objective of this study to determine the antibacterial activity of methanol extract of mangosteen rind against Staphyllococcus aureus and Escherechia coli in vitro.
Antibacterial activity test used is the diffusion wells and paper disc diffusion method. The test results obtained antibacterial activity of methanol extract of mangosteen rind can inhibit the growth of Staphyllococcus aureus at a concentration of 16%, but below its resistance zone diameter Cyprofloxacin. As against Escherichia coli, the methanol extract of mangosteen rind could not inhibit the growth of bacteria.