Open AccessManagement of BRCA1 Mutation Carrier with Breast Cancer
Author(s) -
Inga Melbārde-Gorkuša,
Ilze Štrumfa,
Arvīds Irmejs,
Arnis Āboliņš,
Edvīns Miklaševičs,
Andris Gardovskis,
Signe Subatniece,
Genādijs Trofimovičs,
Jānis Gardovskis
Publication year - 2011
Publication title -
latvijas k̦irurðigijas žurnāls/acta chirurgica latviensis
Language(s) - English
Resource type - Journals
eISSN - 2199-5737
pISSN - 1407-981X
DOI - 10.2478/v10163-012-0029-1
Subject(s) - medicine , breast cancer , mutation , oncology , mastectomy , cancer , prophylactic mastectomy , brca mutation , gene , genetics , biology
Management of BRCA1 Mutation Carrier with Breast Cancer BRCA1 gene mutation carriers face high lifetime risk of breast cancer therefore specific diagnostic features should be considered and individualized treatment strategies should be applied. For BRCA1 mutation carriers with already developed breast cancer, extensive surgery - bilateral mastectomy - could be indicated due to the cancer risk in the contralateral breast.