Open AccessPreparation of Moisturizing Lotion Containing Silkworm (Bombyx mori L.) Sericin Nanoparticles
Author(s) -
Aulia Fikri Hidayat,
Ratih Aryani,
Indrawati Hannisah
Publication year - 2022
Publication title -
ijpst (indonesian journal pharmaceutival science and technology)/ijpst (indonesian journal of pharmaceutical science and technology)
Language(s) - English
Resource type - Journals
eISSN - 2406-856X
pISSN - 2356-1971
DOI - 10.24198/ijpst.v1i1.30486
Subject(s) - sericin , lotion , bombyx mori , chemistry , materials science , moisturizer , silk , chemical engineering , chromatography , food science , organic chemistry , composite material , biochemistry , gene , engineering
Sericin as one of two main proteins in silkworm (Bombyx mori L.) cocoons was found to have the ability to increase skin moisture in cosmetics. The objective of this study was to determine the optimal formula of sericin nanoparticle lotion and the effectiveness of sericin nanoparticle lotion. The formation of sericin nanoparticles was mainly carried out by mixing and stirring mechanism using urea as a crosslinking agent. Temperature and stirring speed were fixed, while stirring duration were varied. Optimal sericin nanoparticles with the average particle size of 701 nm were obtained at 800 rpm stirring for 30 minutes at room temperature. Sericin nanoparticles lotion was then formulated with 5% and 10% sericin nanoparticles. Results showed that lotion containing 5% and 10% sericin nanoparticles significantly increase skin moisture.Keywords: moisturizer, lotion, silkworm, sericin, nanoparticles