Open AccessInvestigation of the Antimicrobial Activity of Some Streptomyces spp. Isolated from Nineveh Province
Author(s) -
Mohammad Bashir Ismail Kassim,
Suha Eleya
Publication year - 2010
Publication title -
maǧallaẗ markaz buḥūṯ al-taqniyyaẗ al-aḥyāʾiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2708-1370
pISSN - 1815-1140
DOI - 10.24126/jobrc.2010.4.2.116
Subject(s) - antimicrobial , antibiotics , streptomyces , microbiology and biotechnology , staphylococcus aureus , antibacterial activity , bacteria , biology , staphylococcus , traditional medicine , medicine , genetics
Atotal of 62 different Streptomyces isolates were recovered from 17 samples of soil collected from different sites of Nineveh Province. Only 23 isolates showed activity against test Gram-positive and Gram-negative bacteria. One isolate showed high antimicrobial activity against Staphylococcus aureus, was selected and identified as Streptomyces lavendulae on the bases of microscopic, morphologic, biochemical tests and its sensitivity to some antibiotics. The bioactive compound produced by S. lavendulae was isolated on TLC plate (Rf 0.85). The UV spectrum of the active compound in methanol showed one peak at 280 nm. From these data it could be concluded that the active compound probably belongs to macrolide antibiotics group.