Emerging variants of novel coronavirus - myth and reality | Zendy

Tanja Jovanović | Zendy; Marko Janković | Zendy; Aleksandra Knežević | Zendy

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Emerging variants of novel coronavirus - myth and reality

Author(s) -

Tanja Jovanović,

Marko Janković,

Aleksandra Knežević

Publication year - 2021

Publication title -

srpski arhiv za celokupno lekarstvo

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.135

H-Index - 17

eISSN - 2406-0895

pISSN - 0370-8179

DOI - 10.2298/sarh210206026j

Subject(s) - medicine , pandemic , virology , coronavirus , covid-19 , transmission (telecommunications) , population , mutation , virus , viral entry , gene , genetics , disease , biology , viral replication , infectious disease (medical specialty) , environmental health , engineering , pathology , electrical engineering

The new coronavirus has crossed the species barrier leading to the pandemic of COVID-19. The lengthy circulation of the virus within the human population has enabled the development of many new viral variants, some of which are conducive to further pathogen spread. Notable variants are those that contain mutations within the S gene, particularly within the region that codes for the receptor-binding domain (RBD) that links to the hACE-2 receptor. These mutations are responsible for increased viral transmission and influence disease severity, reliability of clinical tests, as well as vaccine efficacy. At present, the variant first identified in the United Kingdom poses the greatest threat in Europe.

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