Open Access
Synthesis Characterization and Biological Evaluation of Nitro Amidinothioureas
Author(s) -
B. Jini Kumari,
T. F. Abbs Fen Reji
Publication year - 2022
Publication title -
international journal for research in applied science and engineering technology
Language(s) - English
Resource type - Journals
ISSN - 2321-9653
DOI - 10.22214/ijraset.2022.38801
Subject(s) - antifungal , antimicrobial , nitro , bacteria , combinatorial chemistry , antibacterial activity , chemistry , elemental analysis , stereochemistry , biology , organic chemistry , microbiology and biotechnology , alkyl , genetics
Abstract: The discovery of new bioactive compounds necessarily involves previously diversity studies, because by knowing the type of micro organisms that reside in a certain environment, it is possible to design cultivation techniques adapted for all the microbial communities Present in a certain ambience. Marine organisms possess an inexhaustible source of useful chemical substances for the development of new drugs. The structure of the newly synthesized compounds were elucidated with elementary analysis with IR, 1H NMR and mass spectral data. All the synthesized compounds show weak antioxidant activity and weak antimicrobial and antifungal activity against some bacteria and fungi. Keywords: Amidinothiourea, Antibacterial activity and Anti fungal activity.