Open AccessEFFECTS OF POLYASPARTIC ACID ON REMINERALIZATION OF INTRAFIBRILLAR DENTIN AND SIZE OF HYDROXYAPATITE CRYSTALS
Author(s) -
Waviyatul Ahdi,
Nilakesuma Djauharie,
Ratna Meidyawati,
Ikhwan Muslim
Publication year - 2020
Publication title -
international journal of applied pharmaceutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.238
H-Index - 15
ISSN - 0975-7058
DOI - 10.22159/ijap.2020.v12s2.op-24
Subject(s) - polyaspartic acid , remineralisation , demineralization , chemistry , dentin , transmission electron microscopy , nuclear chemistry , chemical engineering , fluoride , materials science , dentistry , nanotechnology , enamel paint , inorganic chemistry , composite material , organic chemistry , medicine , raw material , engineering
Objective: The objective of this study was to analyze the intrafibrillar remineralization process and the size of hydroxyapatite crystals formed.Methods: The samples were divided into four groups. The control group was immersed in a demineralization solution, whereas the remaining threetreatment groups were immersed in a remineralization solution containing polyaspartic acid for 3, 7, or 14 days. The effect of polyaspartic acid onintrafibrillar remineralization during the polymer-induced liquid-precursor (PILP) process was evaluated using transmission electron microscopy,and the size of hydroxyapatite crystals was examined through X-ray diffraction.Results: Significant differences were detected in the intrafibrillar remineralization between the treatment groups (subjected to remineralization for3, 7, and 14 days) and the demineralized dentin control group. However, no significant differences were detected in the size of hydroxyapatite crystalsbetween the control and the treatment groups.Conclusion: Our data suggest that polyaspartic acid enables intrafibrillar remineralization during the PILP process.