Open AccessSTUDY ON MULTIPOTENT MEDICINAL ASPECTS OF SCHIMA WALLICHII (BARK) FROM NAGALAND, NE INDIA
Author(s) -
Minakshi Bhattacharjee,
Vitolu Sema Y,
Manash Pratimsarma
Publication year - 2019
Publication title -
asian journal of pharmaceutical and clinical research
Language(s) - English
Resource type - Journals
eISSN - 2455-3891
pISSN - 0974-2441
DOI - 10.22159/ajpcr.2019.v12i3.29288
Subject(s) - phytochemical , traditional medicine , bark (sound) , terpenoid , tannin , glycoside , antioxidant , chemistry , biology , botany , medicine , biochemistry , ecology
Objective: The present study focuses on the multipotent medicinal aspects of Schima wallichii bark.
Methods: The ethanol and water extracts of the plant were investigated its phytochemical, antibacterial, antioxidant, and anticoagulant as per the standard method.
Results: S. wallichii bark extract was effective against Staphylococcus aureus. It was also found to be a good antioxidant having an IC50 value of 98.7 in ethanolic extract. Further, the water extract increased in prothrombin time to 57.7 s against normal (12.3 s). The different phytochemicals, namely tannin, saponins, steroids, terpenoids, flavonoids, and glycosides, were present. Since the findings showed very less percent inhibition in comparison to curcumin-treated cells, thus both the extracts were both not effective in the antiproliferative assay.
Conclusion: We conclude that this plant is a good candidate for developing a natural drug.