Open AccessThe Multicenter Italian Trial Assesses the Performance of FDG-PET /CT Related to Pre-Test Cancer Risk in Patients with Solitary Pulmonary Nodules and Introduces a Segmental Thoracic Diagnostic Strategy
Author(s) -
Marco Spadafora,
Laura Evangelista,
Salvatore Fiordoro,
Francesco Porcaro,
Marilena Sicignano,
Luigi Mansi
Publication year - 2020
Publication title -
current radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.586
H-Index - 25
eISSN - 1874-4729
pISSN - 1874-4710
DOI - 10.2174/1874471013666200318142210
Subject(s) - medicine , lung cancer , pet ct , nuclear medicine , radiology , histopathology , solitary pulmonary nodule , nodule (geology) , positron emission tomography , indeterminate , computed tomography , pathology , paleontology , mathematics , biology , pure mathematics
The Italian Tailored Assessment of Lung Indeterminate Accidental Nodule (ITALIAN) trial is a trial drawn to determine the performance of 18F-FDG-PET/CT in patients with solitary pulmonary nodules (SPN), stratified for a different kind of risk. An additional end-point was to compare the diagnostic information and estimated dosimetry, provided by a segmental PET/CT (s-PET/CT) acquisition instead of a whole body PET/CT (wb-PET/CT), in order to evaluate if segmental thoracic PET/CT can be used in patients with SPN.