Open AccessMinocycline Increases in-vitro Cortical Neuronal Cell Survival after Laser Induced Axotomy
Author(s) -
Burak Yuluğ,
Mehmet Ozansoy,
Merve Alokten,
Muzaffer Beyza Ozansoy,
Şeyda Çankaya,
Lütfü Hanoğlu,
Ülkan Kılıç,
Ertuğrul Kılıç
Publication year - 2020
Publication title -
current clinical pharmacology
Language(s) - English
Resource type - Journals
eISSN - 2212-3938
pISSN - 1574-8847
DOI - 10.2174/1574884714666190226093119
Subject(s) - minocycline , neuroprotection , axotomy , medicine , neuroscience , pharmacology , clinical trial , cell survival , in vitro , central nervous system , antibiotics , biology , microbiology and biotechnology , biochemistry
Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials are challenging. In this respect, there are no cases of successful clinical application of such candidate molecules when it comes to human patients.