Open AccessEvaluation of Changes in the Expression Profile of mRNA and Proteinencoding Adiponectin in Ishikawa Cell Line under the Influence of Cisplatin – Preliminary Report
Author(s) -
Robert Kiełabsiński,
Przemysław Kieszkowski,
Beniamin Oskar Grabarek,
Dariusz Boroń
Publication year - 2020
Publication title -
current pharmaceutical biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.555
H-Index - 85
eISSN - 1873-4316
pISSN - 1389-2010
DOI - 10.2174/1389201021666200506074523
Subject(s) - cisplatin , adiponectin , endometrial cancer , medicine , messenger rna , endocrinology , cell culture , drug , cancer , oncology , chemistry , cancer research , pharmacology , biology , chemotherapy , biochemistry , gene , obesity , insulin resistance , genetics
A reduced concentration of adiponectin is considered as an independent factor of the risk of inducing endometrial cancer. Cisplatin is a drug used in the therapy of this type of neoplasm. However, knowledge of the effects of cisplatin on the adiponectin level is still limited.