Open AccessThe clinical significance of natural autoimmunity in patients with adhesive process and external genital endometriosis
Author(s) -
N. R. Karakashian,
Е И Манухина,
M. A. Gevorgyan,
И. Б. Манухин
Publication year - 2016
Publication title -
medicinskij sovet
Language(s) - English
Resource type - Journals
eISSN - 2658-5790
pISSN - 2079-701X
DOI - 10.21518/2079-701x-2016-2-100-101
Subject(s) - medicine , endometriosis , infertility , sex organ , gynecology , gastroenterology , surgery , urology , pregnancy , biology , genetics
The article presents the results of a study of 71 patients with adhesive process diagnosed with external genital endometriosis (EGE) confirmed by laparoscopy. In accordance with the specific serum immunoreactivity evaluation, all patients were divided into 3 groups: Group A (normal response type), Group B (hyper-response type) and group C (hypo-response type). The duration of infertility was on average 6,1 ± 1,3 years. After surgery patients underwent antigonadotropic therapy with 3.75 mg buserelin (a course of 4--6 injections). Against a background of the baseline therapy, all patients in groups B and C underwent correction of immunological disorders. Conclusion: Management of immunological disorders in patients with adhesive process associated with EGE enhances the effectiveness of recovery of the reproductive function