Open Access<p>LINC01087 is Highly Expressed in Breast Cancer and Regulates the Malignant Behavior of Cancer Cells Through miR-335-5p/Rock1</p>
Author(s) -
Jikai She,
Danni Fu,
Zhen Dong,
Guo-Hua Gong,
Bin Zhang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s255994
Subject(s) - cancer research , flow cytometry , reporter gene , cancer , apoptosis , breast cancer , western blot , rock1 , microbiology and biotechnology , biology , medicine , gene expression , gene , signal transduction , biochemistry , rhoa
Long non-coding RNA is involved in the genesis and development of various tumors, and it has been found through database screening that LINC01087 is highly expressed in breast cancer (BC), but mechanisms of LINC01087 in BC are still under investigation. Therefore, this study aimed to study relevant mechanisms of LINC01087 in BC to provide potential therapeutic targets for the disease in clinic practice.