Open AccessUp-Regulation of circEIF6 Contributes to Pancreatic Cancer Development Through Targeting miR-557/SLC7A11/PI3K/AKT Signaling
Author(s) -
Tiequan Zhang,
Mi Li,
Haofeng Lu,
Tao Peng
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s280307
Subject(s) - gene silencing , protein kinase b , pi3k/akt/mtor pathway , pancreatic cancer , gene knockdown , microrna , cancer research , cell growth , biology , apoptosis , signal transduction , microbiology and biotechnology , chemistry , cancer , biochemistry , gene , genetics
Accruing evidences have pointed out that abnormal expression of circular RNAs (circRNAs) was closely related to the development of many malignancies. The present study intended to disclose the role of circRNA eukaryotic translation initiation factor 6 (circEIF6; hsa_circ_0060055) in pancreatic cancer progression.