Open Access<p>miR-124-3p Regulates FGF2–EGFR Pathway to Overcome Pemetrexed Resistance in Lung Adenocarcinoma Cells by Targeting MGAT5</p>
Author(s) -
Jundong Cai,
Jiuning Huang,
Wulong Wang,
Jing Zeng,
Ping Wang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s274192
Subject(s) - pemetrexed , adenocarcinoma , apoptosis , cancer research , epidermal growth factor receptor , flow cytometry , gene silencing , lung cancer , cell growth , mtt assay , cell cycle , biology , chemistry , medicine , microbiology and biotechnology , cancer , cisplatin , oncology , chemotherapy , biochemistry , genetics , gene
To investigate whether miR-124-3p regulates the fibroblast growth factor 2 (FGF2)-epidermal growth factor receptor (EGFR) pathway by targeting MGAT5 to affect the pemetrexed resistance in lung adenocarcinoma cells.