Open AccessThe effect of Nitrofurantoin on liver on Albino mice
Author(s) -
Muna H. Abdul Razzaq,
Mukhtar K. Haba
Publication year - 2014
Publication title -
mağallaẗ baġdād li-l-ʿulūm
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.167
H-Index - 6
eISSN - 2411-7986
pISSN - 2078-8665
DOI - 10.21123/bsj.11.2.913-919
Subject(s) - nitrofurantoin , infiltration (hvac) , pathology , medicine , biology , pharmacology , antibiotics , microbiology and biotechnology , physics , ciprofloxacin , thermodynamics
the current study Included, evaluation the impact of Nitrofurantoin drug on liver in albino mice, 128 male albino mice have been used . Animals treared with (150,200 Mg/Kg) for 8 weeks . NFI caused histological changes in liver represented by , swelling of hepatocytes, disappearance of radial arrangement , vaculation of liver cells , increasing of kupffer cells and appearance of giant cells. NFT caused Congestion of blood vessels and infiltration of inflammatory cells in liver in all used concentrations.