Open Access
Evaluation of anti-cancer effects of root and beet leaf extracts (Beta vulgaris L.) in cervical cancer cells
Author(s) -
Stefhani Andrioli Romero,
Rosângela Maria Neves Bezerra,
Isadora Carolina Betim Pavan,
Ana Paula Morelli,
Luiz Augusto da Silva,
Isabela Fagundes,
Cayo Silva,
Fernando Moreira Simabuco
Publication year - 2020
Publication title -
resumos do...
Language(s) - English
Resource type - Conference proceedings
DOI - 10.20396/revpibic2720191818
Subject(s) - hela , cancer , adjuvant , cervical cancer , cancer cell , mtt assay , viability assay , beta (programming language) , biology , medicine , cell , biochemistry , immunology , computer science , programming language
Cervical cancer is the third cause of cancer between women in 2018. Beetroot has bioactive compounds that have the ability to inhibit the progression of different types of cancer cells. The present study analyzed the possible functional effects of leaf and root extracts of beet as anti-tumor agents in cultures of HeLa cervical cancer cells, testing viability (MTT) and colony formation. The results showed a reduction in viability at concentrations of 10 and 100 ppm and in the diameter of the colonies at the concentration of 10 ppm. This work may contribute for new therapeutic and adjuvant approaches for cervical cancer treatment using beet derived compounds and extracts.