Open AccessSteroidal Saponins from the Seeds of Hyoscyamus Niger L.
Author(s) -
Irina Lunga,
П. К. Кинтя,
S. A. Shvets,
Carla Bassarello,
Sonia Piacente,
Cosimo Pìzza
Publication year - 2008
Publication title -
chemistry journal of moldova
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 5
eISSN - 2345-1688
pISSN - 1857-1727
DOI - 10.19261/cjm.2008.03(1).10
Subject(s) - chemistry , pregnane , glycoside , heteronuclear single quantum coherence spectroscopy , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , carbon 13 nmr , chemical shift , chemical constituents , triterpenoid , organic chemistry , traditional medicine , chromatography , medicine
Ten steroidal saponins have been isolated form the seeds of Hyoscyamus niger L. for the first time and their structures have been elucidated. Seven saponins belong to spirostane series, two are furostane-type and one is pregnane glycoside. Hyoscyamosides B, C and C2 are new steroidal saponins, which have never been reported before in literature. Complete assignments of the 1H and 13C NMR chemical shifts for all these glycosides were achieved by means of one- and two-dimensional NMR techniques, including 1H–1H COSY, HSQC, HMBC and ROESY spectra.