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Evaluation of Preoperative Diflunisal for Postoperative Pain Following Periodontal Surgery
Author(s) -
Minutello James S.,
Newell Donald H.,
Thrash William J.,
Terezhalmy Geza T.
Publication year - 1988
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1988.59.6.390
Subject(s) - diflunisal , medicine , placebo , periodontal surgery , postoperative pain , anesthesia , placebo group , surgery , limiting , preoperative care , pharmacology , mechanical engineering , alternative medicine , pathology , engineering
T he effectiveness of diflunisal as a preoperative medication to reduce pain following periodontal surgery was evaluated. Fifty patients were divided into two groups in a doubleblind random manner: Group one received preoperative difunisal and Group two received preoperative placebo. The preoperative diflunisal group reported significantly less discomfort ( P < 0.05) than the preoperative placebo group and used rescue medication significantly less often ( P < 0.01). Therapeutic doses of diflunisal, given presurgically, are significantly more effective than placebo in limiting postoperative pain associated with periodontal surgery.