Open AccessTHE RESULTS OF HISTOLOGICAL STUDY OF THE IMPACT OF LASER RADIATION IN THE SELECTIVE PHOTOTHERMOLYSIS MODE ON VASCULAR LESIONS IN EXPERIMENT
Author(s) -
Е. А. Морозова,
Морозова Елена Анатольевна,
O. Z. Topolnitsky,
Топольницкий О. З,
В. И. Елисеенко,
Елисеенко В. И,
M. N Kornilev,
Корнильев М. Н
Publication year - 2017
Publication title -
rossijskij stomatologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2413-2934
pISSN - 1728-2802
DOI - 10.18821/1728-2802-2017-21-5-237-241
Subject(s) - laser , irradiation , radiation , materials science , human skin , granulation tissue , blood vessel , epidermis (zoology) , biomedical engineering , pathology , wound healing , optics , anatomy , medicine , surgery , biology , genetics , physics , nuclear physics
This article is dedicated to the increasing of the effectiveness of treatment of patients with vascular lesions of the skin using the radiation of KTP-Nd:YAG laser with a wavelength of532 nm. An experimental research was conducted to study the effect of laser radiation with an energy density of 4, 6, and 8 J/cm2 used on blood vessels ofauricles of experimental animals (rabbits) according to the histological study in dynamics. As a result of the experiment, it was found that laser radiation with a radiation density of up to 4 and 6 J/cm2 does not damage the epidermis of the skin, which indicates the selectivity of the effect on the blood vessels of the rabbit auricles. The histological pattern is distinctive for that ofselective photothermolysis. The processes ofneoangiogenesis, proliferation of fibroblasts, collagen production, fibrillogenesis end with the maturation andfibrous transformation ofthe granulation tissue without its cicatrical deformation. The use of KTP-Nd:YAG laser may increase the quality of treatment of patients with skin lesions.