Open AccessIdentification of risk factors of regional metastasis of differentiated thyroid cancer
Author(s) -
A.-. Kozlovska,
Э. Э. Топузов,
С В Рачинский
Publication year - 2021
Publication title -
zlokačestvennye opuholi
Language(s) - English
Resource type - Journals
eISSN - 2587-6813
pISSN - 2224-5057
DOI - 10.18027/2224-5057-2020-10-3-15-19
Subject(s) - medicine , thyroid cancer , papillary thyroid cancer , thyroidectomy , metastasis , thyroid , cancer , lymph node , stage (stratigraphy) , neck dissection , oncology , dissection (medical) , incidence (geometry) , primary tumor , radiology , paleontology , physics , optics , biology
Diagnostic difficulties of regional metastases, especially lesion of the central neck, is the main problem with choosing the type of surgical intervention for patients with differentiated thyroid cancer diagnosis. The frequency of differentiated thyroid cancer regional metastasis to the neck lymph nodes is about 60 %. This article includes the search and identification of risk factors of differentiated thyroid cancer regional metastases, as well as a review of the literature on this problem. We have analyzed the results of surgical treatment of patients with papillary thyroid cancer of Stage I–III (T1–4aN0–1bM0) who underwent surgical treatment at the St. Petersburg State Healthcare Institution «City Clinical Oncology Center» in 2018–2019. As a result of the study, the data revealed a relationship between regional metastases and intrathyroid vascular invasion of the primary tumor (p 0.05). After the surgical treatment we should focus on the presence of vascular invasion and, if it is detected, perform final thyroidectomy and central lymph node dissection with subsequent radioiodine therapy.