Open AccessNeurobiological mechanisms of the rewars and punishment systems in the brain afteractivation of nucleus accumbens
Author(s) -
Mariya Vladimirovna Sheveleva,
Шевелева Мария Владимировна,
А. А. Лебедев,
Лебедев Андрей Андреевич,
R.O. Roik,
Роик Роман Олегович,
Petr Dmitriyevich Shabanov,
Шабанов Петр Дмитриевич
Publication year - 2013
Publication title -
obzory po kliničeskoj farmakologii i lekarstvennoj terapii
Language(s) - English
Resource type - Journals
eISSN - 2542-1875
pISSN - 1683-4100
DOI - 10.17816/rcf1133-19
Subject(s) - nucleus accumbens , neurochemical , efferent , neuroscience , extended amygdala , amygdala , psychology , reinforcement , punishment (psychology) , reward system , basal ganglia , addiction , afferent , dopamine , central nervous system , developmental psychology , social psychology
The review devoted to neurobiological mechanisms of both positive and negative reinforcement is represented. The key role in these processes plays the nucleus accumbens as a part of the extended amygdala system. The afferent and efferent connections of the n.accumbens, starting mechanisms of the n.accumbens involvement in emotional reactions, interactions between n.accumbens and other structures of the extended amygdala system, and neurochemical organization of the n.accumbens and all system of reinforcement are discussed in the article. The special attention is taken to the n.accumbens participation in addictive behavior.