On the harmful effect of bromine. V. J. Wile (Journ. of Amer. Med. Ass., 1927, No. 5)

Given intravenously bromine only with difficulty passes through the renal epithelium, and therefore bromine salts easily accumulate in the tissues, and displace chlorions, chlorides are quickly excreted, and this causes deficiencies in chlorine. On the contrary, in cases of bromine poisoning, intravenous injection of table salt in physiological solution leads to excretion of bromine from tissues, and sometimes severe irritation of the kidneys is observed.