Cancer care for patients with prostate cancer in the samara region depending on age and method of treatment

Relevance. Prostate cancer (PCa) is the second most common disorder in the male population. According to some authors, prostate cancer is the most commonly defined type of malignant tumor in men. In 2012, the number of men with prostate cancer worldwide reached 1.1 million, which is 15% of all male malignancies. Objective: to assess the survival rates of patients with prostate cancer in the Samara Region over the period 20102014 taking into consideration their age and the given treatment. Materials and methods. 5220 patients with prostate cancer were identified through 20102014. Of these, 4393 people (84.2%) were urban residents, 827 were from rural areas (15.8%). The average age of the subjects was 69.8 years. Results. Analysis of age distribution demonstrated that the largest group consisted of men aged 65-74 years which is 40.7% (2126 patients). It was found that with increasing age, there was a decrease in both HB and CO. Due to the increase in the number of comorbid diseases with the increase of age the observed survival rate appeared significantly lower than the adjusted one. Radical prostatectomy (RP) resulted in high rates of 5-year adjusted survival. Similar results were obtained in the combination of surgical treatment and drug (hormonal) and radiation treatment. Combining RP with radiation or hormone therapy can be used as a multimodal treatment for high and very high risk PCa. In some patients, radiotherapy was included in the treatment regimen, and it proved its effectiveness. Orchiectomy was often used in patients with advanced prostate cancer. However survival rate became less (53.5%). Conclusion. By analyzing survival rates, it is possible to improve the organization of anticancer control by identifying risk groups for the development of the disease, choosing the optimal methods of treatment and their individualization.