Clinical and morphological features, immune profile of renal cell tumors with clear cytoplasm | Zendy

Y. I. Osmanov | Zendy; Е А Коган | Zendy; L. O. Severgina | Zendy; Л. М. Рапопорт | Zendy; N S Aleksandrov | Zendy; Д. Г. Цариченко | Zendy; D. O. Korolyov | Zendy

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Clinical and morphological features, immune profile of renal cell tumors with clear cytoplasm

Author(s) -

Y. I. Osmanov,

Е А Коган,

L. O. Severgina,

Л. М. Рапопорт,

N S Aleksandrov,

Д. Г. Цариченко,

D. O. Korolyov

Publication year - 2019

Publication title -

cancer urology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.125

H-Index - 4

eISSN - 1996-1812

pISSN - 1726-9776

DOI - 10.17650/1726-9776-2019-15-3-126-131

Subject(s) - cytoplasm , renal cell carcinoma , immunohistochemistry , clear cell , medicine , pathology , differential diagnosis , kidney , cell , clear cell renal cell carcinoma , incidence (geometry) , carcinoma , biology , microbiology and biotechnology , genetics , physics , optics

In the structure of oncological morbidity, renal cell carcinoma takes the 10th place among malignant neoplasms. The increase in incidence is observed from the age of 35–40 years and reaches a maximum at the age of 65–70 years. In terms of frequency of occurrence, clear cell renal cell carcinoma is ranked first among all kidney tumors. Meanwhile, due to the high heterogeneity of renal cell carcinomas with clear cytoplasm group, significant differential diagnostic difficulties arise in the morphological verification of these tumors. The article presents all nosological forms of kidney tumors with clear cytoplasm and provides a database of already known immunohistochemical markers for each nosological unit.

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