
Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors
Author(s) -
Huanchen Wang,
Mingsheng Peng,
Yi Chen,
Jianghui Geng,
Howard Robinson,
Miles D. Houslay,
Jun Cai,
Hengming Ke
Publication year - 2007
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/w9qr-pa69
Subject(s) - phosphodiesterase , selectivity , chemistry , computational biology , pharmacology , stereochemistry , biology , biochemistry , enzyme , catalysis