Open AccessCancer-Associated Mutations in the MDM2 Zinc Finger Domain Disrupt Ribosomal Protein Interaction and Attenuate MDM2-Induced p53 Degradation
Author(s) -
Anyi Jin,
Guy Wolf,
Mikael S. Lindström,
C. Deisenroth,
Y. Zhang
Publication year - 2020
Publication title -
unc libraries
Language(s) - English
DOI - 10.17615/cmsa-5s52
Subject(s) - zinc finger , mdm2 , ring finger domain , cancer , degradation (telecommunications) , cancer research , mutation , protein degradation , protein–protein interaction , genetics , chemistry , biology , microbiology and biotechnology , computer science , gene , transcription factor , telecommunications
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