Open AccessMetabolic Effects of D-Chiro-Inositol and Myo-Inositol in Polycystic Ovary Syndrome
Author(s) -
Rabbie K. Hanna,
Tarek Wehbe,
EA Jaoude
Publication year - 2017
Publication title -
international journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
ISSN - 2640-7582
DOI - 10.17352/ijcem.000026
Subject(s) - polycystic ovary , insulin resistance , metformin , metabolic syndrome , medicine , endocrinology , hirsutism , infertility , inositol , hyperandrogenism , anovulation , endocrine system , obesity , insulin , biology , hormone , pregnancy , receptor , genetics
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. The pathogenesis has not been fully deciphered. PCOS is associated with insulin resistance (IR), menstrual irregularities, cardiovascular disease, obesity, hirsutism, infertility, and endometrial cancer. The use of D-chiro-inositol (DCI) for the treatment of IR in PCOS has been controversial with contradictory data being published. Our objective is to evaluate the effect of DCI combined with myo-inositol (MI), and metformin on the metabolic outcomes of PCOS in a Lebanese women cohort.
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