Open AccessThe Finding of N‐Nitrosodimethylamine in Common Medicines
Author(s) -
Adamson Richard H.,
Chabner Bruce A.
Publication year - 2020
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2020-0142
Subject(s) - n nitrosodimethylamine , medicine , ranitidine , intensive care medicine , environmental health , pharmacology , carcinogen , genetics , biology
The FDA has ordered the withdrawal of all ranitidine products from the marketplace based on recent findings of increased and unacceptable levels of N‐nitrosodimethylamine (NDMA). This commentary reviews the sources and properties of NDMA, assesses the dangers it poses, and suggests measures to mitigate contamination.