Open AccessRole of epicardial adipose tissue in the development of atrial fibrillation in hypertensive patients
Author(s) -
В. И. Подзолков,
А. И. Тарзиманова,
А. Е. Брагина,
К К Осадчий,
R. Gataulin,
К. А. Оганесян,
З. Б. Джафарова
Publication year - 2020
Publication title -
kardiovaskulârnaâ terapiâ i profilaktika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 16
eISSN - 2619-0125
pISSN - 1728-8800
DOI - 10.15829/1728-8800-2020-2707
Subject(s) - medicine , epicardial adipose tissue , atrial fibrillation , cardiology , adipose tissue , multislice computed tomography , obesity , risk factor , epicardial fat , multislice , paroxysmal atrial fibrillation , computed tomography , radiology
Obesity is a progressing epidemic, the prevalence of which has doubled over the past 30 years. The distribution of adipose tissue is an important factor in predicting the risk of cardiovascular events. The most significant inflammatory activity is characteristic of epicardial adipose tissue (EAT), the role of which in the development of atrial fibrillation (AF) remains a subject of discussion. Aim. To study the effect of EAT size on the development of AF in hypertensive (HTN) patients. Material and methods. The study included 95 patients with HTN aged 38-72 years (mean age, 61,5±1,8 years), including 45 patients with paroxysmal AF (group I) and 50 patients in the comparison group (group II). In order to assess the severity of visceral obesity, all patients underwent a general examination and echocardiography. To determine the EAT volume, cardiac multislice computed tomography was performed. Results. Echocardiography revealed that the EAT thickness was significantly greater in hypertensive patients with paroxysmal AF than in the comparison group: 11,6±0,8 and 8,6±0,4 mm, respectively (p 10 mm and volume >6 ml can serve as integral markers of the onset of paroxysmal AF. Conclusion. Integral markers of AF in hypertensive patients are an increase in the EAT thickness >10 mm (odds ratio, 4,1; 95% confidence interval, 1,1-5,6) and volume >6 ml (odds ratio 3,7; 95%, confidence interval 1,0-4,2).