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HEME OXYGENASE-2 NEURONS BRAIN AND SPINAL CORD OF HUMAN
Author(s) -
V. M. Chertok,
A. E. Kotsyuba,
E. P. Kotsyuba
Publication year - 2012
Publication title -
annals of the russian academy of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 15
eISSN - 2414-3545
pISSN - 0869-6047
DOI - 10.15690/vramn.v67i6.282
Subject(s) - spinal cord , heme oxygenase , central nervous system , heme , methylene blue , neuroscience , neuron , sensory system , chemistry , immune system , enzyme , biology , biochemistry , immunology , catalysis , photocatalysis
Immune localization of heme oxygenase-2 in neurons of some nuclei of the spinal cord and brain stem in 6 men 18–44 years old who died from causes unrelated to injury of central nervous system was studied. Neurons with positive reaction are determined for all studied regions of the brain where their contents in various nuclei ranging from 0,5 to 16% of the total number of cells detected by methylene blue. In all the sensory nuclei there is a high proportion of small neurons with a high or moderate density of reaction produc deposits. Large cells of motor nuclei often exhibit negative or low intensive enzyme reaction. 

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