Reduced microvascular perfusion and reactivity in adult GH deficient patients is restored by GH replacement | Zendy

Václav Hána | Zendy; Martin Prázný | Zendy; J Marek | Zendy; J Škrha | Zendy; V Justová | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Reduced microvascular perfusion and reactivity in adult GH deficient patients is restored by GH replacement

Author(s) -

Václav Hána,

Martin Prázný,

J Marek,

J Škrha,

V Justová

Publication year - 2002

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.0.1470333

Subject(s) - perfusion , medicine , reactive hyperemia , microcirculation , endocrinology , vasodilation , laser doppler velocimetry , endothelial dysfunction , cardiology , blood flow , growth hormone deficiency , hormone , growth hormone

An increased cardiovascular risk and mortality in hypopituitary patients receiving conventional hormonal treatment without GH replacement have been shown in several studies. Various atherogenic risk factors including endothelial dysfunction - an early event in the atherogenesis - are more expressed in adults with GH-deficiency (GHD). Changes in microcirculation and vascular reactivity could represent an early marker of developing vascular changes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research