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The IGF system in patients with type 2 diabetes: associations with markers of cardiovascular target organ damage
Author(s) -
Rikke Hjortebjerg,
Esben Laugesen,
Pernille Høyem,
Claus Oxvig,
Brian StausbølGrøn,
Søren Tang Knudsen,
Won Yong Kim,
Per Løgstrup Poulsen,
Troels Krarup Hansen,
Mette Bjerre,
Jan Frystyk
Publication year - 2017
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-16-0940
Subject(s) - medicine , subclinical infection , pulse wave velocity , endocrinology , type 2 diabetes , diabetes mellitus , arterial stiffness , cardiology , insulin like growth factor , growth factor , blood pressure , receptor
Perturbations in the insulin-like growth factor (IGF) system may contribute to the accelerated cardiovascular disease (CVD) that occurs in patients with type 2 diabetes (T2D). However, it remains unknown whether the IGF system is also involved in the development of early, subclinical CVD. We characterised the IGF system in T2D patients and matched controls and examined the associations with markers of subclinical target organ damage.

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