Open AccessExpression Profile of Mouse Gm20594, Nuclear-Encoded Humanin-Like Gene
Author(s) -
Jihye Kim,
Jong-Whan Choi,
Jun Namkung
Publication year - 2021
Publication title -
journal of lifestyle medicine
Language(s) - English
Resource type - Journals
eISSN - 2288-1557
pISSN - 2234-8549
DOI - 10.15280/jlm.2021.11.1.13
Subject(s) - mitochondrial biogenesis , biology , downregulation and upregulation , mitochondrial dna , prdm16 , brown adipose tissue , gene expression , mitochondrion , microbiology and biotechnology , adipocyte , adipose tissue , gene , genetics , endocrinology
Mitochondrial-derived peptides (MDPs) such as MOTS-c and humanin have been studied for their cytoprotective functions. In mice, humanin-encoding Mtrnr2 is a mitochondrial pseudogene, and the humanin-like peptide is encoded by the nuclear Gm20594 gene. However, endogenous tissue-specific expression profiles of Gm20594 have not yet been identified.