Structural covariance of neostriatal and limbic regions in patients with obsessive–compulsive disorder | Zendy

Marta Subirà | Zendy; Marta Cano | Zendy; Stella J. de Wit | Zendy; Pino Alonso | Zendy; Narcı́s Cardoner | Zendy; Marcelo Q. Hoexter | Zendy; Jun Soo Kwon | Zendy; Takashi Nakamae | Zendy; Christine Löchner | Zendy; João Ricardo Sato | Zendy; Wi Hoon Jung | Zendy; Jin Narumoto | Zendy; Dan J. Stein | Zendy; Jesús Pujol | Zendy; David MataixCols | Zendy; Dick J. Veltman | Zendy; José M. Menchón | Zendy; Odile A. van den Heuvel | Zendy; Carles SorianoMas | Zendy

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Structural covariance of neostriatal and limbic regions in patients with obsessive–compulsive disorder

Author(s) -

Marta Subirà,

Marta Cano,

Stella J. de Wit,

Pino Alonso,

Narcı́s Cardoner,

Marcelo Q. Hoexter,

Jun Soo Kwon,

Takashi Nakamae,

Christine Löchner,

João Ricardo Sato,

Wi Hoon Jung,

Jin Narumoto,

Dan J. Stein,

Jesús Pujol,

David MataixCols,

Dick J. Veltman,

José M. Menchón,

Odile A. van den Heuvel,

Carles SorianoMas

Publication year - 2016

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.150012

Subject(s) - putamen , neuroscience , psychology , middle frontal gyrus , neuroimaging , statistical parametric mapping , voxel , caudate nucleus , prefrontal cortex , functional magnetic resonance imaging , medicine , magnetic resonance imaging , radiology , cognition

Frontostriatal and frontoamygdalar connectivity alterations in patients with obsessive-compulsive disorder (OCD) have been typically described in functional neuroimaging studies. However, structural covariance, or volumetric correlations across distant brain regions, also provides network-level information. Altered structural covariance has been described in patients with different psychiatric disorders, including OCD, but to our knowledge, alterations within frontostriatal and frontoamygdalar circuits have not been explored.

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