Open AccessDesign, Synthesis, Characterization and Biological Activities of Recent Isatin Derivatives with Proven Pharmacophoric Moiety
Author(s) -
Ruchi Bhatnagar,
Jaya Pandey,
Deepa Panhekar
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22823
Subject(s) - isatin , chemistry , moiety , antibacterial activity , antifungal , imine , combinatorial chemistry , stereochemistry , organic chemistry , bacteria , microbiology and biotechnology , biology , genetics , catalysis
Isatin derivatives, alkylated with proven pharmacophoric moiety were synthesized for variousbiodynamic activities. To enhance some biodynamic properties like antibacterial and antifungal, imineformation with various compounds at C3 was analyzed. The isatin derivatives were characterized andexamined for various biodynamic activities on bacteria, fungus and cancer cell lines.